Introduction So far, no detailed evaluation of the results of neuromuscular therapy with functional electrical stimulation combined with kinesiotherapy in long-term observation of post-stroke deficits has been performed. Aim The aim was to compare results of neuromuscular functional electrical stimulation algorithm (NMFES) associated with uniform system of kinesiotherapy based mainly on proprioceptive neuromuscular facilitation (PNF) procedures versus the same system of applied kinesiotherapy alone in two months follow up. Material and Methods The same set of clinical studies has been applied to a group of 25 healthy volunteers once as well as three times (T0-at hospital ward up to 7 days after incident, T1- after 21 days of treatment at hospital ward, T2-after 62 days of home-based treatment) to the 50 patients after ischemic stroke divided in two groups, 25 subjects each (NMFES+K and K groups). Evaluation of treatment effects in two groups of patients was performed with NIHSS scale, Lovett’s scale and Ashworth’s scale. Results After 60 days of applied treatment, only patients of NMFES+K group represented a statistical significant decrease of NIHSS scale score indicating the retirement of stroke symptoms. The symptom of increased muscle tension evaluated in Ashwort’s scale in patients of NMFES+K group significantly decreased but not in patients of K group. The muscle force of extensor muscles of upper and lower extremities significantly increased only in patients of NMFES+K group. Conclusions Proposed personalized, safe and controlled in use NMFES electrostimulation algorithm gives better and long-lasting functional effects than previously used as a standard.