Movement is an inseparable part of human life, therefore it is one of the most natural remedies. Its effects on the nervous system are both physiological and epigenetic nature, therefore, movement affects the brain in a multidimensional and multimodal manner. It turns out, however, that the neurorehabilitation therapist may also affect the nervous system through specific motor acts as a result of proprioceptors stimulation, the relationship between coordination abilities and cognitive functions, and the involvement of individual areas of the central nervous system in intensive and effective work. This paper presents the current state of knowledge regarding the influence of movement on the functioning of the nervous system, and in particular the brain, at the cognitive, systemic and molecular levels.